Joint & Muscle Comfort

How Topical Pain Relief Works

Topical products are applied to the skin, but they do not all work in the same way. Understanding the main categories makes product comparisons much easier.

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Topical NSAIDs

Diclofenac is an NSAID used topically in certain arthritis products. This category targets inflammation and pain through NSAID pharmacology.

Counterirritants

Menthol and camphor create cooling, warming or tingling sensations that can change pain perception.

Capsaicin

Capsaicin affects pain-signaling pathways and can cause a burning sensation, especially when treatment begins.

Anesthetics

Lidocaine temporarily numbs local tissue and is used in a range of topical products.

Botanical-style creams

These combine plant extracts, oils and supporting ingredients. Their marketing may emphasize natural ingredients, but the evidence for the exact finished formula must be considered separately.

Related guides

Sources & further reading